Men’s preconception support

Fatherhood starts before day one.

Sire 1 Fertility Support for Men - 1 Month Supply

Prenatal support for men. One 30-day bottle with CoQ10, NAC, L-carnitine and selected vitamins and minerals.

$49.95 every month

Free shipping · contiguous U.S.

About $1.67/daily serving · before tax

Renews at $49.95 every month until canceled, plus applicable tax. Shipping outside the contiguous U.S. is calculated at checkout. Manage or cancel via your confirmation email. Subscription terms.

Includes the Quick-start Essentials digital guide.

Made in a GMP facility
Made in the USA
Made in an FDA-registered facility

Facility registration is not FDA approval of this product. About registration

Free shipping on every deliveryContiguous U.S. (48 states + DC).

Standard shipping. Usually dispatches in 1–3 business days; estimated delivery 3–10 business days after dispatch. Carrier delays may occur. Alaska, Hawaii, territories and other destinations outside the contiguous U.S. are excluded from this offer; available rates appear at checkout. Applicable tax is additional. Read the full policy

30-day first-bottle guaranteeFirst subscription bottle, even if opened.

Request within 30 days of delivery. Refund covers the bottle price and tax; shipping and renewals are excluded. Read the full policy

 Compare one-time options

Three capsules daily · 30 days per bottle

Sire 1 Fertility Support for Men - 1 Month Supply
SIRE IOne bottle per subscription delivery
3 capsules daily30 days per bottleCoQ10 · NAC · L-carnitine

It takes two to prepare

You’re preparing for a baby. Where do you start?

For men, choosing a supplement can mean comparing ingredients, doses and several separate bottles. SIRE brings its selected ingredients into one daily serving, with the details in full view.

Start by understanding the formula. Then choose the delivery option that fits your plans.

Meet the founders
Scene of two adults holding hands beside a notebook and a SIRE I bottle
The future is something you prepare for together.
Sire 1 Fertility Support for Men - 1 Month SupplyOne bottle · 30 daily servings

Meet SIRE I

CoQ10. NAC. L-carnitine. Already together.

Three ingredients often discussed in male preconception research, alongside lycopene, zinc, selenium and other listed ingredients. One bottle, with every amount disclosed.

One serving to keep track of

Three capsules daily. Each bottle contains 90 capsules—30 daily servings.

Inspect the whole formula

See the ingredient forms, exact amounts and full Supplement Facts before you decide.

Choose how you reorder

Subscribe for $49.95 every month, or choose a one-time supply. Subscriptions and three-packs include free contiguous-U.S. standard shipping. Applicable tax is additional.

$49.95 every month

Free shipping · contiguous U.S.

Renews at $49.95 every month until canceled, plus applicable tax. Shipping outside the contiguous U.S. is calculated at checkout. Manage or cancel via your confirmation email. Subscription terms.

Includes the Quick-start Essentials digital guide.

Shipping policyReturns and guarantees

Why this formula

Cellular energy. Antioxidant nutrition.

CoQ10 and L-carnitine have roles in cellular energy. NAC supplies a building block for glutathione, an antioxidant made by the body. Explore the ingredients, their research and the exact amounts in SIRE.

Explore the full formula & research
CoQ10
Coenzyme

CoQ10

250 mg per serving, as ubiquinone. CoQ10 participates in cellular energy production and acts as an antioxidant. It has been studied in men with reduced sperm motility.

Study details & context

Randomized human trial

Balercia et al. studied 200 mg of CoQ10 daily for six months in 60 men with reduced sperm motility. The trial examined semen measures; it did not test SIRE, which contains 250 mg per serving.

A small, selected clinical population and semen endpoints do not establish a pregnancy benefit or the effects of SIRE I.

Read the peer-reviewed paperBalercia et al. · Fertility and Sterility · 2009
N-acetylcysteine (NAC)
Cysteine derivative

N-acetylcysteine (NAC)

600 mg per serving. NAC supplies cysteine for glutathione, one of the body’s antioxidants. Research has examined oxidative stress and semen quality in selected men with infertility.

Study details & context

Before-and-after human study

Jannatifar et al. followed 50 men with abnormal sperm motility and morphology taking 600 mg of NAC daily for three months, comparing semen and oxidative-stress measures with their pretreatment results.

The reported methods compare participants with their own baseline, without a placebo comparison. This cannot isolate the effect of NAC or predict SIRE outcomes.

Read the peer-reviewed paperJannatifar et al. · Reproductive Biology and Endocrinology · 2019
L-carnitine tartrate
Carnitine

L-carnitine tartrate

500 mg per serving, as L-carnitine tartrate. Carnitine helps transport fatty acids into mitochondria, where cells produce energy.

Study details & context

Randomized crossover trial

Lenzi et al. compared 2 g of L-carnitine daily with placebo in selected men with infertility. This is not equivalent to SIRE’s 500 mg of L-carnitine tartrate.

The paper studied L-carnitine, not the finished SIRE formula. Its regimen should not be assumed equivalent to L-carnitine tartrate in this product.

Read the peer-reviewed paperLenzi et al. · Fertility and Sterility · 2003
View Supplement Facts
Read label as text

Serving Size: 3 Capsules
Servings Per Container: 30

Amount Per Serving · %Daily Value

Vitamin A (as Retinyl Palmitate and Beta-Carotene)
6.45 mg · 716%
Vitamin E (as d-Alpha Tocopheryl Succinate)
18 mg · 120%
Vitamin B6 (as Pyridoxal-5-Phosphate)
6 mg · 354%
Folate (as L-5 Methyltetrahydrofolate)
900 mcg DFE · 225%
Vitamin B12 (as Methylcobalamin)
160 mcg · 6,667%
Selenium (as Selenium Glycinate)
120 mcg · 218%
Copper (as Copper Glycinate)
1 mg · 111%
Zinc (as Zinc Glycinate)
24 mg · 218%
Lycopene
24 mg · †
N-Acetyl Cysteine (NAC)
600 mg · †
L-Carnitine Tartrate
500 mg · †
Ashwagandha (Withania somnifera) Extract
250 mg · †
Alpha-Lipoic Acid
250 mg · †
Coenzyme Q10 (Ubiquinone)
250 mg · †

† Daily Value not established.

Other Ingredients: Gelatin Capsule, Magnesium Stearate, Silicon Dioxide.

Ingredient studies do not establish the effects of SIRE I or guarantee fertility outcomes. SIRE I is not a fertility treatment.

Follow your bottle’s Supplement Facts, directions and cautions.

Why prepare ahead

Think in months. Start with today.

Sperm take roughly two to three months to develop and mature. That makes the months before conception a useful time to review nutrition, daily habits and your individual health.

01

Give preparation time.

Use the months before trying to review your nutrition, habits and health with a qualified healthcare professional.

02

Look beyond the supplement.

Food, movement, rest and individual medical advice remain part of the plan. A bottle cannot replace them.

03

Plan without a promised deadline.

Sperm development is a biological timeline. It does not establish when—or whether—a supplement will change fertility outcomes.

About sperm development · ASRM

A 90-day supply is a planning choice, not a promise of fertility results. Supplements should not delay assessment or treatment.

SIRE bottle beside a glass of water in warm morning light

Make it part of your day

One daily serving. One place in your day.

Three capsules from one bottle. Follow your label’s directions and cautions, and choose a daily moment you can remember.

  1. Choose a daily moment.

    Keep your bottle somewhere that fits your day and away from children. Follow the storage instructions on the label.

  2. Three capsules daily.

    A bottle provides 30 daily servings. Follow the directions and cautions on your label.

  3. Keep your next bottle ready.

    Choose recurring delivery every month, or order three bottles together once. Same formula. Different ways to plan.

Follow the directions and cautions on your label. Ask your healthcare professional about suitability, medications and other supplements.

Fatherhood starts before day one.

Sebastian & Matt · Co-founders

The people behind SIRE

A father’s question. A nutritionist’s perspective.

When Sebastian and his wife were preparing for a baby, he wanted a tangible way for men to take part in the preparation, too.

He worked with Matt, a holistic nutritionist, on SIRE’s formula. Their aim: bring selected ingredients into one daily supplement, with a label you can understand and a routine you can follow.

Meet the founders

Why trust SIRE

Clear facts before you commit.

Read the label. Meet the people behind the formula. Know what your first order covers.

01

Every amount, in plain sight.

All 14 ingredients have named amounts on the Supplement Facts label. Review the forms, serving size and other ingredients before you decide.

Read the complete label
Read label as text

Serving Size: 3 Capsules
Servings Per Container: 30

Amount Per Serving · %Daily Value

Vitamin A (as Retinyl Palmitate and Beta-Carotene)
6.45 mg · 716%
Vitamin E (as d-Alpha Tocopheryl Succinate)
18 mg · 120%
Vitamin B6 (as Pyridoxal-5-Phosphate)
6 mg · 354%
Folate (as L-5 Methyltetrahydrofolate)
900 mcg DFE · 225%
Vitamin B12 (as Methylcobalamin)
160 mcg · 6,667%
Selenium (as Selenium Glycinate)
120 mcg · 218%
Copper (as Copper Glycinate)
1 mg · 111%
Zinc (as Zinc Glycinate)
24 mg · 218%
Lycopene
24 mg · †
N-Acetyl Cysteine (NAC)
600 mg · †
L-Carnitine Tartrate
500 mg · †
Ashwagandha (Withania somnifera) Extract
250 mg · †
Alpha-Lipoic Acid
250 mg · †
Coenzyme Q10 (Ubiquinone)
250 mg · †

† Daily Value not established.

Other Ingredients: Gelatin Capsule, Magnesium Stearate, Silicon Dioxide.

02

People you can put a name to.

SIRE was co-founded by Sebastian, a father, and Matt, a holistic nutritionist who collaborated on the formula. Have a question? Contact Sebastian directly.

Email Sebastian
03

A defined first-order guarantee.

Your first subscription bottle has a 30-day money-back guarantee from delivery, even if opened. The bottle price and tax are covered; shipping and renewals are excluded.

Read guarantee eligibility and terms

SIRE I

Start with one bottle. Choose how you reorder.

Subscribe for $49.95 every month—$15 less per bottle than buying once at $64.95. Prefer one delivery? Choose a single bottle or three-bottle supply. Subscriptions and three-packs include free contiguous-U.S. standard shipping. Applicable tax is additional.

SIRE I single bottle — 30-day supply
Choose your supply

Renews at $49.95 every month until canceled, plus applicable tax. Shipping outside the contiguous U.S. is calculated at checkout. Manage or cancel via your confirmation email. Subscription terms.

Includes the Quick-start Essentials digital guide.

Made in a GMP facility
Made in the USA
Made in an FDA-registered facility

Facility registration is not FDA approval of this product. About registration

Free shipping on every deliveryContiguous U.S. (48 states + DC).

Standard shipping. Usually dispatches in 1–3 business days; estimated delivery 3–10 business days after dispatch. Carrier delays may occur. Alaska, Hawaii, territories and other destinations outside the contiguous U.S. are excluded from this offer; available rates appear at checkout. Applicable tax is additional. Read the full policy

30-day first-bottle guaranteeFirst subscription bottle, even if opened.

Request within 30 days of delivery. Refund covers the bottle price and tax; shipping and renewals are excluded. Read the full policy

Question & Answer

Find the details on your formula, delivery and first-order guarantee.

Ask us a question
Why choose SIRE?

SIRE combines CoQ10, NAC and L-carnitine tartrate with selected vitamins, minerals and other ingredients in one three-capsule serving. The full label shows every amount. Co-founder Matt, a holistic nutritionist, collaborated on the formula; Sebastian brings his experience as a father. Choose a subscription or one-time supply based on how you want to reorder.

Why these ingredients?

The combination brings together ingredients involved in cellular energy and antioxidant processes, including CoQ10, NAC and L-carnitine. Some have been studied in selected men with infertility. Those studies inform the ingredient discussion; they do not establish the effects of SIRE’s finished formula.

How soon should I expect results?

SIRE does not have an established timeline for changes in sperm parameters or pregnancy outcomes. Sperm development takes roughly two to three months, but that is not a guarantee that a supplement will help. Do not delay fertility assessment or treatment while taking supplements.

How does the subscription work?

One 30-day bottle is delivered and billed every month until cancelled. The subscription is $49.95 per delivery, plus applicable tax, with free standard shipping to the contiguous U.S. Other U.S. shipping rates are shown at checkout. Manage or cancel using the link in your subscription confirmation email.

Can I order without subscribing?

Yes. Choose one bottle for $64.95 once or three bottles for $164.95 once. Neither one-time option renews automatically.

How do I take SIRE-1?

The bottle provides 90 capsules, a 30-day supply at three capsules daily. Follow the directions and cautions on your product label and advice from your healthcare professional.

What does the guarantee cover?

The current policy covers the first single-bottle subscription order for 30 days from delivery, even if opened, refunding the bottle price and applicable tax. Shipping and renewals are excluded. The first three-bottle order has a separate 90-day guarantee. Single one-time bottles follow the standard return conditions. Read the full policy for eligibility and exclusions.

What does shipping cost?

Free standard shipping on subscriptions and three-packs to the contiguous U.S. (48 states + DC). One-time single bottles ship for $5.95 to those destinations. Outside this area, available rates are shown at checkout. Applicable tax is additional.

Is it suitable for vegetarians or vegans?

No. The current label lists a gelatin capsule. Review all ingredients and consult a qualified healthcare professional if you have allergies or dietary restrictions.

Can I take it alongside other supplements?

Ask a qualified healthcare professional to review the combination, particularly if you take medication or have a health condition. Follow the label’s cautions.

Start with one bottle.

$49.95 every month

Free shipping · contiguous U.S.

Renews at $49.95 every month until canceled, plus applicable tax. Shipping outside the contiguous U.S. is calculated at checkout. Manage or cancel via your confirmation email. Subscription terms.

Includes the Quick-start Essentials digital guide.

Shipping policyReturns and guarantees
 Compare one-time options